Recovery and healing · Peptide Therapy
TB-500 in Tampa, FL
TB-500 (a thymosin beta-4 fragment) is a peptide that may support tissue repair, wound healing and muscle recovery. The research behind it is mostly lab and animal work, so a licensed provider goes over what is known before anything is prescribed.
Padgett Medical Center in Tampa, Florida offers BPC-157, TB-500, KPV, MOTS-c, Semax and Epitalon, prescribed after a free consultation with a licensed provider and compounded by a licensed U.S. compounding pharmacy.
- The consultation is free. You only pay for your peptides if you start.
- New patients: 10% off the first peptide order when you book online with a card on file
- In person in Tampa or telehealth anywhere in Florida
TB-500 at Padgett
From $300
Every product and price is listed below.
- Consultation
- Free
- Form
- An injection
- Prescribed by
- A licensed provider
- Compounded by
- A licensed U.S. compounding pharmacy
Compounded peptides have not been approved by the FDA.
Pricing
TB-500 price in Tampa
The consultation is free. You only pay for your peptides if you start. TB-500 at Padgett Medical Center in Tampa costs $300 (injection, 15 mg in a 4 mL vial, 1 vial).
| Product | Order | Price | Card on file10% off first order, new patients |
|---|---|---|---|
| Injection15 mg in a 4 mL vial | 1 vial | $300 | $270 |
New patients who book online with a card on file get 10% off their first peptide order ($300 becomes $270). Nothing is charged when you book, and current patients pay the listed price.
Your provider confirms the right product at your consultation. Prices are subject to change. Compounded for you by a licensed U.S. compounding pharmacy: about our partner pharmacies.
Compounded peptides have not been approved by the FDA.
What is TB-500?
TB-500 (also written TB500 or TB 500) is a lab-made peptide of 7 amino acids (written Ac-LKKTETQ). It copies one small active region, amino acids 17 to 23, of thymosin beta-4, which is why it is often called a thymosin beta-4 fragment. Thymosin beta-4 is a natural protein of 43 amino acids found in almost every cell and in blood, saliva, tears and wound fluid, and it plays a role in tissue repair.
People often confuse TB-500 with full-length thymosin beta-4, but they are different molecules, and research on the full protein does not automatically apply to TB-500. TB-500 first drew scientific attention from anti-doping labs, which identified it in products suspected of misuse in sport, including horse racing.
Who TB-500 may help
TB-500 may help with:
- Tissue repair after an injury
- Wound healing
- Inflammation
- Muscle recovery after exercise or a strain
No human study has tested TB-500 for these uses yet. They come from the biology of thymosin beta-4 and a small amount of animal research, so they are possibilities, not promises.
How TB-500 may work
The 7 amino acids in TB-500 include the part of thymosin beta-4 that binds actin, a protein cells use to change shape and move. By managing actin, thymosin beta-4 helps cells migrate into a wound. Thymosin beta-4 is also linked to new blood vessel growth, lower inflammation and less scar formation, and reviews describe the 17 to 23 region as the part tied to blood vessel growth and cell migration.
It is not settled whether TB-500 itself does all of this. FDA reviewers noted that the acetyl group on TB-500 may change how the fragment behaves. In one 2024 lab study, TB-500 did not speed closure of scratched skin cells, while one of its breakdown products did.
What the research shows
What has been seen in cells and animals, what has been seen in people, and what has not been shown yet.
Lab and animal studies
Most of this research is on full-length thymosin beta-4, not TB-500. In animal studies, thymosin beta-4 supported healing of skin wounds and the cornea and helped protect the heart after injury.
Studies of the TB-500 fragment itself are few. In aged mice, a topical form of the 17 to 23 fragment (without the acetyl group) improved wound closure. In a 2026 rat study of repaired Achilles tendons, TB-500 injections were linked to stronger tendons and better tissue structure at four weeks, and adding BPC-157 gave no extra benefit.
Studies in people
In 2026, FDA reviewers found no published human studies of TB-500 by any route and no human safety data. Full-length thymosin beta-4 has been tested in people: an IV safety study in 40 healthy volunteers found it well tolerated over 14 days of dosing, and eye drop and topical forms have been studied for dry eye, corneal wounds and skin ulcers, with encouraging but mixed results.
A 2026 orthopaedic review stressed that these results cannot be applied to TB-500, because no one has shown that TB-500 works the same way as the full protein. No human study has tested TB-500 for tendon, ligament or muscle recovery.
The bottom line
The biology of thymosin beta-4 and a small amount of animal research suggest TB-500 may support tissue repair, wound healing and muscle recovery. There is no human trial evidence for TB-500 itself.
TB-500 is not FDA-approved. In July 2026 an FDA advisory committee voted 8 to 6, with 1 abstention, to recommend adding TB-500 to the list of substances pharmacies may use in compounding. FDA staff had recommended against it. The vote is advisory.
How TB-500 is taken
At Padgett, TB-500 comes as an injection. Your provider sets the dose; the general pattern for each product is below.
- Injection, 15 mg in a 4 mL vial1 vial. Twice a week.
If TB-500 is right for you, your provider sets your dose and schedule at your consultation and goes over how to use it.
TB-500 side effects and safety
Your provider reviews your health history and every medicine you take before prescribing.
Possible side effects
- Headaches
- Fatigue
- Nausea
- Dizziness
- Injection site reaction
- Allergic reaction
- Anxiety
- Fluid retention
Tell your provider about any new symptom, or call (813) 888-7710. In a medical emergency, call 911.
Who should not take TB-500
- People who are pregnant, trying to become pregnant, or breastfeeding (no human data and no reproductive studies)
- Anyone with active cancer, a history of cancer, or an undiagnosed lump or growth (thymosin beta-4 is linked to tumor cell migration and blood vessel growth in lab and animal studies)
- Children and teens under 18 (not studied)
- Competitive athletes subject to drug testing (prohibited at all times by the World Anti-Doping Agency)
- Anyone who has had an allergic reaction to TB-500 or any ingredient in the product
This is not a complete list. Your provider reviews your full health history before prescribing.
What is known about safety
TB-500's side effects in people are not well known because it has not been studied in people. FDA's 2026 review found no published animal toxicity studies of TB-500 and no human safety data. FDA's adverse event database had no TB-500 reports through March 2025. Another FDA report linked a "research use only" BPC-157 and TB-500 blend to darkening of the skin and gums. In healthy volunteers given full-length thymosin beta-4 by IV, side effects were infrequent and mild to moderate, but that result cannot be assumed to apply to TB-500.
Cancer is a theoretical concern. Thymosin beta-4 promotes cell migration and new blood vessel growth. In a mouse study, raising thymosin beta-4 in melanoma cells increased tumor size, tumor blood vessels and the number of lung metastases, and higher thymosin beta-4 has been linked to more aggressive colorectal cancer cells in lab and mouse studies. No one knows whether injected TB-500 carries this risk.
FDA notes that injected peptides may pose a significant risk of immune reactions, and that impurities or clumping of the peptide can raise it. Thymosin beta-4 and its derivatives, including TB-500, are on the World Anti-Doping Agency's 2026 Prohibited List (class S2), banned in and out of competition.
Medicines and interactions
No drug interaction studies have been done for TB-500 in people. TB-500 is often combined with BPC-157 and other peptides, and none of these combinations have been tested in people. At FDA's 2026 advisory meeting, a panel member raised concern about use in combination with other peptides. Tell your provider about every medicine and supplement you take, especially any cancer treatment.
TB-500 vs BPC-157
Both are studied for recovery and healing, and each is a separate product. No one has studied the two together in people, so your provider decides whether one, both or neither makes sense for you.
| Topic | TB-500 | BPC-157 |
|---|---|---|
| Also called | Thymosin Beta-4 fragment, TB500, TB 500 | Body Protection Compound-157, BPC 157, BPC157 |
| Studied for | May support tissue repair, wound healing and muscle recovery. | May support healing of tendons, ligaments and injuries, and the gut lining. |
| Forms at Padgett | an injection | an oral capsule or an injection |
| Price | $300 | $12 per capsule or $275 |
| Evidence | The biology of thymosin beta-4 and a small amount of animal research suggest TB-500 may support tissue repair, wound healing and muscle recovery. There is no human trial evidence for TB-500 itself. | Animal research suggests BPC-157 may support tissue repair and the gut lining. It has not been shown to work in well-designed human trials. |
Peptide quality
Prescribed and pharmacy-compounded, not "research grade"
At Padgett Medical Center in Tampa, peptides are prescribed only after a consultation with a licensed medical provider, and each one is compounded for the individual patient by a licensed U.S. compounding pharmacy. That is not the same as the "research grade" or "research use only" peptides sold online, which are labeled not for human use and are not made or checked to pharmacy standards for people, so there is no way to be sure of their strength, purity or sterility, or how well they will work.
| Prescribed and pharmacy-compounded at Padgett | Research-grade / research use only |
|---|---|
| Who decides it's right for you | |
| A licensed provider reviews your health history at a free consultation before anything is prescribed. | No one. You pick a vial from a website. |
| Where it's made | |
| A licensed U.S. compounding pharmacy, made for you to a prescription. | Unknown manufacturers, often overseas, selling "for research use only". |
| Meant for people? | |
| Yes. Compounded for a named patient to take. | No. Labeled not for human use or consumption. |
| Strength, purity and sterility | |
| Held to pharmacy compounding standards. | Not verified to pharmacy standards, so the dose and what else is in the vial are unknown. |
| Support while you take it | |
| Tell your provider about any side effect or question while you take it; they can adjust your plan. | You're on your own. |
| Price | |
| Published on every peptide page, and the consultation is free. | Cheap per vial, but you can't know what you're paying for. |
Regulatory status
Are these peptides FDA-approved? Where things stand in November 2026
No. BPC-157, TB-500, KPV, MOTS-c, Semax and Epitalon are not FDA-approved, and compounded medications are not FDA-approved. The FDA does not review compounded drugs for safety, effectiveness or quality before they are prescribed.
On October 30, 2026, the U.S. Department of Health and Human Services (HHS) published a notice in the Federal Register about an interim policy for compounding these six peptides. It says HHS does not intend to take enforcement action against state-licensed pharmacies and licensed physicians that compound them for individual patients while the FDA completes formal rulemaking, as long as specific conditions are met. Those conditions include:
- A prescription for each patient
- A bulk ingredient from an FDA-registered manufacturer, tested for identity, purity, strength and contaminants
- One peptide per product, so no blends
- Only the forms the policy lists for each peptide (for example, Semax only as a nasal spray)
- For forms taken by mouth, documentation that enough of the peptide is absorbed in people
- Reporting serious side effects to the FDA
The policy is temporary and may change. The Federal Register notice announced it as a draft, open for public comment into mid-November 2026, so HHS may revise it, and HHS has said it may revisit it if safety or quality problems come up. The policy does not mean these peptides are proven safe or effective. It does not cover peptides sold as research chemicals or supplements.
Before it, in July 2026, an FDA advisory committee voted to recommend adding these six peptides to the list of substances pharmacies may compound from. FDA staff had recommended against it, citing limited human safety data, and the vote is advisory.
At Padgett Medical Center, peptides are prescribed only after a consultation with a licensed provider, and each one is compounded for you by a licensed U.S. compounding pharmacy.
Sources: Federal Register: notice of the HHS interim policy on 503A compounding of certain peptides, 91 FR 68526 (October 30, 2026), FR Doc. 2026-22192; Holland & Knight: HHS issues interim enforcement discretion policy for compounding of 6 peptides (November 4, 2026); FDA: Certain bulk drug substances for use in compounding that may present significant safety risks (content current April 22, 2026); Healio: FDA committee recommends looser restrictions for several peptides (July 24, 2026).
TB-500 questions, answered
What is TB-500? Is it the same as thymosin beta-4?
TB-500 is a lab-made peptide of 7 amino acids. It copies a small active region of thymosin beta-4, a natural protein the body uses in tissue repair. It is not the same as full-length thymosin beta-4, which has 43 amino acids, and research on the full protein does not automatically apply to TB-500.
Has TB-500 been studied in people?
Not yet. In 2026, FDA reviewers found no published human studies of TB-500 by any route. Most of the research behind it comes from lab and animal studies of full-length thymosin beta-4, plus a few animal studies of TB-500. That research suggests TB-500 may support tissue repair, wound healing and muscle recovery, but no one has confirmed these effects in people.
Is TB-500 FDA-approved?
No. TB-500 is not FDA-approved for any use, and compounded peptides are not FDA-approved drugs. At Padgett, a licensed provider reviews your health history at a free consultation before anything is prescribed, and a licensed U.S. compounding pharmacy compounds it for you.
Is TB-500 legal in Florida?
TB-500 is not FDA-approved, so the answer depends on how it is made and prescribed. On October 30, 2026, the U.S. Department of Health and Human Services (HHS) published a notice in the Federal Register about an interim policy for TB-500 and five other peptides. It says HHS does not intend to take enforcement action against state-licensed pharmacies and licensed physicians that compound them for individual patients while the FDA completes formal rulemaking, as long as conditions are met, including a prescription for each patient, a tested ingredient from an FDA-registered manufacturer and one peptide per product. For TB-500, the policy covers only injections under the skin or into a muscle. The policy does not cover products sold online as "research use only". It is temporary and may change, and Florida pharmacy and medical rules still apply. At Padgett Medical Center, TB-500 is prescribed after a consultation with a licensed provider and compounded by a licensed U.S. compounding pharmacy.
Where can I get TB-500 in Tampa?
At Padgett Medical Center, 6904 W. Linebaugh Ave, Tampa, FL 33625. You start with a free consultation with a licensed provider, in person at our Tampa clinic or by telehealth from anywhere in Florida. If TB-500 is right for you, a licensed U.S. compounding pharmacy compounds it for you, and you only pay for it if you start.
What are the side effects of TB-500?
TB-500 has not been studied in people, so its side effects are not well known. With any injected peptide, possible problems include redness, swelling or pain at the injection site, and allergic reactions. FDA has noted that injected peptides can trigger immune reactions. Long-term effects are unknown, so tell your provider about any new symptom.
Can I take TB-500 if I have had cancer?
TB-500 is generally not advised if you have active cancer or a history of cancer. Thymosin beta-4, the protein TB-500 comes from, helps cells move and helps grow new blood vessels. In lab and mouse studies, higher thymosin beta-4 in cancer cells was linked to faster tumor growth and spread. No one knows whether TB-500 injections carry this risk in people, so tell your provider about any cancer history.
TB-500 vs BPC-157: can I take them together?
The two are often paired online, but no one has studied the combination in people. In a 2026 rat study of Achilles tendon repair, combining them gave no extra benefit over either peptide alone. One FDA report described skin and gum darkening in a person using an online "research use only" blend of the two. The HHS interim policy also covers one peptide per product, so blends are not part of it. Your provider decides whether one, both or neither makes sense for you.
How is Padgett's TB-500 different from "research grade" TB-500 sold online?
"Research grade" or "research use only" TB-500 is labeled not for human use. It is not made or checked to pharmacy standards for people, so its strength, purity and sterility are unknown. A 2026 orthopaedic review raised concerns about the identity, purity, concentration and sterility of products marketed as TB-500. At Padgett, TB-500 is prescribed only after a consultation with a licensed provider, and a licensed U.S. compounding pharmacy compounds it for you. Research-grade vs pharmacy-compounded peptides explains the difference.
How much does TB-500 cost?
The consultation is free, and nothing is charged when you book. You only pay for TB-500 if you start it. TB-500 at Padgett Medical Center in Tampa costs $300 (injection, 15 mg in a 4 mL vial, 1 vial). New patients who book online with a card on file get 10% off their first peptide order ($300 becomes $270). Nothing is charged when you book, and current patients pay the listed price.
Other peptides we offer
Each is prescribed after the same free consultation. You can ask about more than one.
- Recovery and healingBPC-157Also called Body Protection Compound-157, BPC 157May support healing of tendons, ligaments and injuries, and the gut lining.From $275BPC-157 in Tampa
- Gut health and inflammationKPVAlso called Lysine-Proline-Valine, KPV peptideMay calm gut and skin inflammation and support the intestinal barrier.From $90KPV in Tampa
- Metabolism and energyMOTS-cAlso called MOTS-C, MOTScMay support insulin sensitivity, metabolism and exercise endurance.From $400MOTS-c in Tampa
- Focus and cognitionSemaxAlso called Semax nasal spray, Semax peptideMay support focus, memory and mental clarity, and ease brain fog.From $125Semax in Tampa
- Sleep and healthy agingEpitalonAlso called Epithalon, EpitaloneMay support sleep quality and healthy cellular aging.From $250Epitalon in Tampa
Peptide guides
TB-500 and peptide therapy near you
Sources
- FDA briefing document: TB-500-related bulk drug substances, Pharmacy Compounding Advisory Committee, July 23-24, 2026
- Tham A, Hodgkins CW, Kennedy JG. Investigational peptides in orthopaedic practice: evidence, safety, and patient counseling for BPC-157, thymosin beta-4, and TB-500. J Am Acad Orthop Surg, 2026 (PMID 42937313)
- Esposito S, et al. Synthesis and characterization of the N-terminal acetylated 17-23 fragment of thymosin beta 4 identified in TB-500. Drug Testing and Analysis, 2012 (PMID 22962027)
- Xing Y, et al. Progress on the function and application of thymosin beta 4. Frontiers in Endocrinology, 2021 (PMC8724243)
- Cha HJ, Jeong MJ, Kleinman HK. Role of thymosin beta4 in tumor metastasis and angiogenesis. J Natl Cancer Inst, 2003 (PMID 14625258)
- Healio: FDA committee recommends looser restrictions for several peptides (July 24, 2026)
- Federal Register: notice of the HHS interim policy on 503A compounding of certain peptides, 91 FR 68526 (October 30, 2026), FR Doc. 2026-22192
Free peptide consultation
Talk with a licensed provider about TB-500
The consultation is free. You only pay for your peptides if you start. In person at our Tampa clinic or by telehealth anywhere in Florida, and new patients who book online with a card on file get 10% off their first peptide order.
Interested in more than one peptide? Pick them all when you book.
* Compounded peptides have not been approved by the FDA. They have not been reviewed by the FDA for safety, effectiveness or quality, and none of the peptides on this site is an FDA-approved drug. The benefits described are possibilities from research, not promises, and results vary from person to person. A licensed provider decides at your consultation whether a peptide is right for you. This page is educational and is not medical advice.